Glacier moraine formation-mimicking colloidal particle assembly in microchanneled, bioactive hydrogel for guided vascular network construction.
نویسندگان
چکیده
This study demonstrates that a new method to align microparticles releasing bioactive molecules in microchannels of a hydrogel allows the guiding of growth direction and spacing of vascular networks.
منابع مشابه
Vascularized adipose tissue grafts from human mesenchymal stem cells with bioactive cues and microchannel conduits.
Vascularization is critical to the survival of engineered tissues. This study combined biophysical and bioactive approaches to induce neovascularization in vivo. Further, we tested the effects of engineered vascularization on adipose tissue grafts. Hydrogel cylinders were fabricated from poly(ethylene glycol) diacrylate (PEG) in four configurations: PEG alone, PEG with basic fibroblast growth f...
متن کاملScheduling of Multiple Autonomous Guided Vehicles for an Assembly Line Using Minimum Cost Network Flow
This paper proposed a parallel automated assembly line system to produce multiple products having multiple autonomous guided vehicles (AGVs). Several assembly lines are configured to produce multiple products in which the technologies of machines are shared among the assembly lines when required. The transportation between the stations in an assembly line (intra assembly line) and among station...
متن کاملIn-situ Formation of Hydrogel Membranes and Growth of Colloidal Crystals in Microchannels Using One Step Stamping
This paper reports a novel method for in-situ formation of hydrogel membranes and geometrically controlled selfassembly of colloidal crystals in microchannels using one step stamping. The simple elastomeric stamp was made of PDMS from SU-8 patterned master using standard soft lithography. Then the selective hydrophobic pattern on the PDMS stamp surface was achieved using Pluronic F127 coating a...
متن کاملHypoxia-mimicking bioactive glass/collagen glycosaminoglycan composite scaffolds to enhance angiogenesis and bone repair.
One of the biggest challenges in regenerative medicine is promoting sufficient vascularisation of tissue-engineered constructs. One approach to overcome this challenge is to target the cellular hypoxia inducible factor (HIF-1α) pathway, which responds to low oxygen concentration (hypoxia) and results in the activation of numerous pro-angiogenic genes including vascular endothelial growth factor...
متن کاملAnatomy of terminal moraine segments and implied lake stability on Ngozumpa Glacier, Nepal, from electrical resistivity tomography (ERT)
Moraine-dammed lakes at debris-covered glaciers are becoming increasingly common and pose significant outburst flood hazards if the dam is breached. While moraine subsurface structure and internal processes are likely to influence dam stability, only few sites have so far been investigated. We conducted electrical resistivity tomography (ERT) surveys at two sites on the terminal moraine complex...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Advanced healthcare materials
دوره 4 2 شماره
صفحات -
تاریخ انتشار 2015